| Glucose 1-phosphate | |
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Glucose 1-phosphate |
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| Identifiers | |
| CAS number | 59-56-3 |
| PubChem | 65533 |
| ChemSpider | 388311 |
| MeSH | glucose-1-phosphate |
| ChEBI | CHEBI:16077 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C6H13O9P |
| Molar mass | 260.136 |
| (verify) (what is: /?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.
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In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.
To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.
In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.
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